Labelling of dying neurones by peroxidase injected intravascularly in chick embryos.

@article{Clarke1982LabellingOD,
  title={Labelling of dying neurones by peroxidase injected intravascularly in chick embryos.},
  author={Peter G. H. Clarke},
  journal={Neuroscience letters},
  year={1982},
  volume={30 3},
  pages={223-8}
}
Three lines of evidence indicate that intravascularly injected horseradish peroxidase labels dying neurones selectively in the developing isthmo-optic nucleus: (i) in unoperated embryos, labelled neurones are found only during the period of normal neuronal death; (ii) some of the labelled neurones are manifestly necrotic; (iii) an intraocular injection of colchicine causes essentially all the isthmo-optic neurones to degenerate, and then they almost all take up peroxidase. However… CONTINUE READING