Labeling strategies with F-18 for positron emission tomography imaging.

  title={Labeling strategies with F-18 for positron emission tomography imaging.},
  author={Yonghong Gu and Dong Huang and Zhiguo Liu and Jiaguo Huang and Wenbin Zeng},
  journal={Medicinal chemistry (Shariqah (United Arab Emirates))},
  volume={7 5},
The labeling of probes with fluorine-18 [(18)F, β(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the fluorine-18 labeling of probes for PET imaging. Problems and issues relating to the practical production of fluorine-18 currently in widespread use are also discussed. 

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