Labeling of skeletal myoblasts with a novel oxygen-sensing spin probe for noninvasive monitoring of in situ oxygenation and cell therapy in heart.

@article{Wisel2007LabelingOS,
  title={Labeling of skeletal myoblasts with a novel oxygen-sensing spin probe for noninvasive monitoring of in situ oxygenation and cell therapy in heart.},
  author={Sheik Wisel and Simi M. Chacko and Muthulakshmi L Kuppusamy and R. Thava Prakasa Pandian and Mahmood Khan and Vijay Kumar Kutala and Richard W. Burry and Benjamin Chih-An Sun and Pawel Kwiatkowski and Periannan Kuppusamy},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={292 3},
  pages={
          H1254-61
        }
}
We report the labeling (internalization) of skeletal myoblasts (SMs) with a novel class of oxygen-sensing paramagnetic spin probe for noninvasive tracking and in situ monitoring of oxygenation in stem cell therapy using electron paramagnetic resonance (EPR) spectroscopy. SM cells were isolated from thigh muscle biopsies of mice and propagated in culture. Labeling of SM cells with the probe was achieved by coincubating the cells with submicron-sized (270 +/- 120 nm) particulates of the probe in… CONTINUE READING

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Myocardial oxygenation and functional recovery in infarct rat hearts transplanted with mesenchymal stem cells.

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  • 2009
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Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function.

  • American journal of physiology. Heart and circulatory physiology
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