Labeled antigens and antibodies: the evolution of magic markers and magic bullets

@article{Silverstein2004LabeledAA,
  title={Labeled antigens and antibodies: the evolution of magic markers and magic bullets},
  author={A. Silverstein},
  journal={Nature Immunology},
  year={2004},
  volume={5},
  pages={1211-1217}
}
The ability to label antigens and antibodies with simple chemicals and even with whole proteins fostered new approaches to basic studies of the immune system as well as new methods of immunodiagnosis and immunotherapy. This was especially true following the introduction of monoclonal antibodies, which enhanced the specificity of many of these applications. The uses to which these labeled immunoreagents were put were legion, and those who employed them might come from any field of biology or… Expand
25 Citations
Targeted Therapy of Cancer: New Prospects for Antibodies and Immunoconjugates
  • 215
Antibody Labeling with Fluorescent Dyes Using Magnetic Protein A and Protein G Beads.
Complexity of anti-immunosenescence strategies in humans.
  • 67
On-bead antibody-small molecule conjugation using high-capacity magnetic beads.
  • 12
Immunological Methods for Nursing Research: From Cells to Systems
  • 4
  • Highly Influenced
...
1
2
3
...

References

SHOWING 1-10 OF 106 REFERENCES
Immunotoxins: selection of cell-surface antigens and their corresponding monoclonal antibodies.
  • 5
Immunotoxins: an update.
  • 159
Chelates and antibodies: current methods and new directions.
  • 25
The genetic engineering of monoclonal antibodies.
  • 65
Immunological Specificity
  • 223
Direct immunoenzyme double staining applicable for monoclonal antibodies
  • 26
...
1
2
3
4
5
...