Label-free ultrarapid spheroid formation in microfluidic chip using magneto-Archimedes effect

@article{Akiyama2012LabelfreeUS,
  title={Label-free ultrarapid spheroid formation in microfluidic chip using magneto-Archimedes effect},
  author={Yusuke Akiyama and Keisuke Morishima},
  journal={2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS)},
  year={2012},
  pages={116-119}
}
This paper demonstrates formation of a spheroid array in a microfluidic chip with neither cell labeling nor a specific microchannel pattern. Label-free ultrarapid magnetic cell manipulation is made possible by adding a paramagnetic salt to the culture medium to enhance the diamagnetic property of the cells. The cells in the paramagnetic medium aggregate… CONTINUE READING