Label-free imaging of intracellular motility by low-coherent quantitative phase microscopy.

@article{Yamauchi2011LabelfreeIO,
  title={Label-free imaging of intracellular motility by low-coherent quantitative phase microscopy.},
  author={Toyohiko Yamauchi and Hidenao Iwai and Yutaka Yamashita},
  journal={Optics express},
  year={2011},
  volume={19 6},
  pages={
          5536-50
        }
}
The subject study demonstrates the imaging of cell activity by quantitatively assessing the motion of intracellular organelles and cell plasma membranes without any contrast agent. The low-coherent interferometric technique and phase-referenced phase shifting technique were integrated to reveal the depth-resolved distribution of intracellular motility. The transversal and vertical spatial resolutions were 0.56 μm and 0.93 μm, respectively, and the mechanical stability of the system was 1.2 nm… CONTINUE READING

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