Label-free imaging of acanthamoeba using multimodal nonlinear optical microscopy

@inproceedings{Kobayashi2018LabelfreeIO,
  title={Label-free imaging of acanthamoeba using multimodal nonlinear optical microscopy},
  author={Tsubasa Kobayashi and Yu-Rok Cha and Y. Kaji and T. Oshika and P. Leproux and V. Couderc and H. Kano},
  booktitle={BiOS},
  year={2018}
}
Acanthamoeba keratitis is a disease in which amoebae named Acanthamoeba invade the cornea of an eye. To diagnose this disease before it becomes serious, it is important to detect the cyst state of Acanthamoeba in the early stage of infection. In the present study, we explored spectroscopic signitures of the cyst state of Acanthamoeba using multimodal nonlinear optical microscopy with the channels of multiplex coherent anti-Stokes Raman scattering (CARS), second harmonic generation (SHG), and… Expand

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