Label-free detection of bacteria by electrochemical impedance spectroscopy: comparison to surface plasmon resonance.

@article{Maalouf2007LabelfreeDO,
  title={Label-free detection of bacteria by electrochemical impedance spectroscopy: comparison to surface plasmon resonance.},
  author={Rita Maalouf and Chantal Fournier-Wirth and Joliette Coste and Hanna Ch{\'e}bib and Youssef Sa{\"i}kali and Olivier Vittori and Abdelhamid Errachid and Jean-Pierre Cloarec and Claude Martelet and Nicole Jaffrezic‐Renault},
  journal={Analytical chemistry},
  year={2007},
  volume={79 13},
  pages={
          4879-86
        }
}
The low but known risk of bacterial contamination has emerged as the greatest residual threat of transfusion-transmitted diseases. Label-free detection of a bacterial model, Escherichia coli, is performed using nonfaradic electrochemical impedance spectroscopy (EIS). Biotinylated polyclonal anti-E. coli is linked to a mixed self-assembled monolayer (SAM) on a gold electrode through a strong biotin-neutravidin interaction. The binding of one antibody molecule for 3.6 neutravidin molecules is… 
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