Label-free biosensing by means of periodic lattices of high aspect ratio SU-8 nano-pillars.

@article{Holgado2010LabelfreeBB,
  title={Label-free biosensing by means of periodic lattices of high aspect ratio SU-8 nano-pillars.},
  author={Miguel Holgado and Carlos Angulo Barrios and F J Fern{\'a}ndez Ortega and Francisco J. Sanza and Rafael Casquel and Mar{\'i}a F. Laguna and Mar{\'i}a Jos{\'e} Ba{\~n}uls and David L{\'o}pez-Romero and Rosa Puchades and {\'A}ngel Maquieira},
  journal={Biosensors & bioelectronics},
  year={2010},
  volume={25 12},
  pages={2553-8}
}
We developed biophotonic sensing arrays of 60x60 microm(2) made of periodic lattices of high aspect ratio SU-8 nano-pillars in order to demonstrate their capability for label-free molecule detection, as well as the sensitivity enhancement in comparison with a single layer of SU-8. The biophotonic sensing arrays, that we call BICELLs (Biophotonic sensing cells), are interrogated vertically by using micron spot size Fourier transform visible and IR spectrometry (FT-VIS-IR). We monitored the… CONTINUE READING
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