Label-free Raman monitoring of extracellular matrix formation in three-dimensional polymeric scaffolds.

Abstract

Monitoring extracellular matrix (ECM) components is one of the key methods used to determine tissue quality in three-dimensional scaffolds for regenerative medicine and clinical purposes. Raman spectroscopy can be used for non-invasive sensing of cellular and ECM biochemistry. We have investigated the use of conventional (confocal and semiconfocal) Raman… (More)
DOI: 10.1098/rsif.2013.0464

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