Label-free LC-MSMS analysis of vitreous from autoimmune uveitis reveals a significant decrease in secreted Wnt signalling inhibitors DKK3 and SFRP2.

@article{Hauck2012LabelfreeLA,
  title={Label-free LC-MSMS analysis of vitreous from autoimmune uveitis reveals a significant decrease in secreted Wnt signalling inhibitors DKK3 and SFRP2.},
  author={Stefanie M Hauck and Florian Hofmaier and Johannes Dietter and Margarete E. Swadzba and Marcel Blindert and Barbara Amann and Jennifer Behler and Elisabeth Kremmer and Marius Ueffing and Cornelia A Deeg},
  journal={Journal of proteomics},
  year={2012},
  volume={75 14},
  pages={4545-54}
}
Equine recurrent uveitis is a severe and frequent blinding disease in horses which presents with auto-reactive invading T-cells, resulting in the destruction of the inner eye. Infiltration of inflammatory cells into the retina and vitreous is driven by currently unknown guidance cues, however surgical removal of the vitreous (vitrectomy) has proven… CONTINUE READING