Label-free DNA detection with a nanogap embedded complementary metal oxide semiconductor.

@article{Kim2011LabelfreeDD,
  title={Label-free DNA detection with a nanogap embedded complementary metal oxide semiconductor.},
  author={Chang-Hoon Kim and Cheulhee Jung and Kyung-Bok Lee and Hyun Gyu Park and Yang-Kyu Choi},
  journal={Nanotechnology},
  year={2011},
  volume={22 13},
  pages={
          135502
        }
}
A nanogap embedded complementary metal oxide semiconductor (NeCMOS) is demonstrated as a proof-of-concept for label-free detection of DNA sequence. When a partially carved nanogap between a gate and a silicon channel is filled with charged biomolecules, the gate dielectric constant and charges are changed. When the gate oxide thickness reduces, the threshold voltage is significantly affected by a change of the charges, whereas it is scarcely influenced by a change of the dielectric constant. In… CONTINUE READING
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