Labdane diterpenes from Chloranthus serratus.
@article{Zhang2013LabdaneDF, title={Labdane diterpenes from Chloranthus serratus.}, author={Mi Zhang and Junsong Wang and J. Luo and Pengran Wang and Chao Guo and L. Kong}, journal={Fitoterapia}, year={2013}, volume={91}, pages={ 95-99 } }
Five new labdane diterpenes (1-5), serralabdanes A-E, were isolated from the whole plant of Chloranthus serratus. Their structures were elucidated by spectroscopic methods, and the absolute configuration of the 12,13-diol moiety in serralabdane C (3) was determined by observing the induced circular dichroism (ICD) after addition of dimolybdenum teracetate in DMSO solution. Serralabdanes A-E (1-5) showed inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells.
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