• Corpus ID: 149748

LUNG FUNCTION STUDIES . II . THE RESPIRATORY DEAD SPACE 192

@inproceedings{Fowler2004LUNGFS,
  title={LUNG FUNCTION STUDIES . II . THE RESPIRATORY DEAD SPACE 192},
  author={W. S. Fowler},
  year={2004}
}
C ERTAIN methods of estimating pulmonary ventilatory efficiency are limited by the accuracy of the measurement of respiratory dead space (I, 2). Krogh and Lindhard measured the physiological dead space and concluded that it varied within narrow limits during changes in lung inflation (3); on the other hand, Haldane and Priestley (4) maintained that the dead space might increase as much as 8~0 cc. during maximal lung inflation. Though subsequent investigations (5, 6) have in general confirmed… 

Figures and Tables from this paper

Time and volume dependence of dead space in healthy and surfactant-depleted rat lungs during spontaneous breathing and mechanical ventilation.
TLDR
A new mainstream capnograph designed for the utilization in small animals like rats is developed and used for determination of dead space volume in healthy and surfactant-depleted rats during spontaneous breathing and mechanical ventilation at three different tidal volumes.
A precision measure of anatomic dead space: Theory
TLDR
The method remains relatively accurate when significant fluctuations of tidal volume occur between breaths in the presence of severe ventilation maldistribution such as inflation of a small compartment to twice its original size.
Dead space
TLDR
The combination of airflow and mainstream capnography monitoring allows calculation of breath by breath CO2 production and pulmonary dead space and the use of volumetric capnographic is clinically more profitable than time-based capnographers.
Monitoring dead space during recruitment and PEEP titration in an experimental model
TLDR
Monitoring of dead space was useful for detecting lung collapse and for establishing open-lung PEEP after a recruitment maneuver and the receiver operating characteristics curve demonstrated a high specificity and sensitivity of VDalv/VTalv and Pa-etCO2.
States of low pulmonary blood flow can be detected non-invasively at the bedside measuring alveolar dead space
TLDR
The ratio of alveolar dead space toAlveolar tidal volume (VDalv/VTalv) can detect states of low pulmonary blood flow (PBF) in a non-invasive way to detect in vivo manipulates PBF in vivo.
Effects of positive end-expiratory pressure on dead space and its partitions in acute lung injury
TLDR
Alveolar VD is large and does not vary systematically with PEEP in patients with various degrees of ALI, and individual measurements show a diverse response to PEEP, suggesting Respiratory mechanics were of no help in optimising PEEP with regard to gas exchange.
Labeled carbon dioxide (C18O2): an indicator gas for phase II in expirograms.
TLDR
Overall, power moment analysis provides a more comprehensive view on phase II of single-breath expirograms than conventional dead space volume determinations and may be useful for respiratory physiology studies as well as for the study of diseased lungs.
Validation of Bohr dead space measured by volumetric capnography
TLDR
Close linear correlations between the two methods for calculating VDBohr can be calculated with accuracy using volumetric capnography, and PACO2 values obtained from the standard alveolar air formula are found.
Effect of pulmonary perfusion on the slopes of single-breath test of CO2.
TLDR
Normalizing S(II) and S(III) eliminated the effect of changes in the magnitude of PBF on the shape of the SBT-CO(2) curve.
STRUCTURAL AND FUNCTIONAL BASIS OF VENTILATION , PERFUSION , AND GAS EXCHANGE
TLDR
The lung exists for gas exchange, that is, the transfer of oxygen from the air to the blood and carbon dioxide from the blood to the air, through ventilation, a process of sequential inhalation and exhalation of gas.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 23 REFERENCES
Science in World War II. Boston: Little Brown 81 Co., I: 314
  • Science in World War II. Boston: Little Brown 81 Co., I: 314
  • 1948
J. C&z. Invest
  • J. C&z. Invest
  • 1947
HROGH , A . AND J . LINDHARD . J . Physiol
  • Proc . Staff Meetings Mayo Clinic
  • 1946
Proc. Staff Meetings Mayo Clinic 21: I I 2
  • Proc. Staff Meetings Mayo Clinic 21: I I 2
  • 1946
Staff Meetings Mayo Clinic 21: I I 2
  • 1946
Unequal Ventilation of Dijerent Parts of the Sting
  • Unequal Ventilation of Dijerent Parts of the Sting
  • 1946
Acta Med. Sand
  • Acta Med. Sand
  • 1944
J. C&z. Invest
  • J. C&z. Invest
  • 1944
Philadelphia: Lea & Febiger
  • Philadelphia: Lea & Febiger
  • 1944
...
1
2
3
...