LTP in cultured hippocampal-entorhinal cortex slices from young adult (P25-30) rats.

@article{Leutgeb2003LTPIC,
  title={LTP in cultured hippocampal-entorhinal cortex slices from young adult (P25-30) rats.},
  author={Jill K Leutgeb and Julietta U. Frey and Thomas Behnisch},
  journal={Journal of neuroscience methods},
  year={2003},
  volume={130 1},
  pages={19-32}
}
Cultured hippocampal neurons and immature organotypic slice cultures overcome temporal limitations of acute hippocampal slices and have been useful for investigating long-lasting plasticity. Difficulties with culturing adult neurons have restricted such studies to preparations from embryonic, perinatal, and juvenile tissue. By improving the methods for culturing and maintaining hippocampal-entorhinal cortex slices obtained from mature rats (P25-30), we show that their use in long-term… CONTINUE READING