LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication.


LSm1-7 complexes promote cellular mRNA degradation, in addition to translation and replication of positive-strand RNA viruses such as the Brome mosaic virus (BMV). Yet, how LSm1-7 complexes act on their targets remains elusive. Here, we report that reconstituted recombinant LSm1-7 complexes directly bind to two distinct RNA-target sequences in the BMV… (More)
DOI: 10.1261/rna.1712910


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