• Corpus ID: 52105165

LSPb 1 inhibits the proliferation of laryngeal squamous cell cancer and neonatal vessels via HMGB 1 / NFB pathway

  title={LSPb 1 inhibits the proliferation of laryngeal squamous cell cancer and neonatal vessels via HMGB 1 / NFB pathway},
  author={Weiming Hu and Jiaying Lin and Lizhong Su and Ming Liu},
This study aims to explore the effect of Lepista sordida polysaccharide (LSPb) 1 on angiogenesis in nude mice tumor transplantation model of laryngeal squamous cell cancer with drug resistance, as well as investigate the mechanism of HMGB1 (high mobility group box1 protein)/NF-κB signal pathway on the regulation of invasion and metastasis of laryngeal squamous cell carcinoma. The nude mice were raised to a certain stage followed by randomly divided into LSPb1 treatment group and normal control… 

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