LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects

@article{Gasser2015LSDassistedPF,
  title={LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects},
  author={Peter Gasser and Katharina Kirchner and Torsten Passie},
  journal={Journal of Psychopharmacology},
  year={2015},
  volume={29},
  pages={57 - 68}
}
Objective: A recently published study showed the safety and efficacy of LSD-assisted psychotherapy in patients with anxiety associated with life-threatening diseases. Participants of this study were included in a prospective follow-up. Method: 12 months after finishing LSD psychotherapy, 10 participants were tested for anxiety (STAI) and participated in a semi-structured interview. A Qualitative Content Analysis (QCA) was carried out on the interviews to elaborate about LSD effects and lasting… 
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References

SHOWING 1-10 OF 81 REFERENCES
LSD-assisted psychotherapy in patients with terminal cancer.
TLDR
A clinical study exploring the potential of a complex psychotherapeutic program utilizing psychedelic compounds to alleviate the emotional and physical suffering of cancer patients found that there was a definite reduction of the narcotic medication.
Safety and Efficacy of Lysergic Acid Diethylamide-Assisted Psychotherapy for Anxiety Associated With Life-threatening Diseases
TLDR
Results indicate that when administered safely in a methodologically rigorous medically supervised psychotherapeutic setting, LSD can reduce anxiety, suggesting that larger controlled studies are warranted.
Long lasting effects of LSD on normals.
TLDR
This report is a report of a study designed to measure personality, attitude, value, interest, and performance changes resulting from the administration of LSD to normals, and whether a dramatic drug-induced experience—which tempo¬ rarily dissolves the primacy of habitual self image, environment, beliefs, and values—will have a lasting impact on the individual's personality.
Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer.
TLDR
This study established the feasibility and safety of administering moderate doses of psilocybin to patients with advanced-stage cancer and anxiety and revealed a positive trend toward improved mood and anxiety.
Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin.
TLDR
Evidence that psilocybin enhances autobiographical recollection implies that it may be useful in psychotherapy either as a tool to facilitate the recall of salient memories or to reverse negative cognitive biases.
The experimental use of psychedelic (LSD) psychotherapy.
The history of research with psychedelic drugs has produced a variety of methods for their use and conflicting claims about results. First came the wave of excitement among experimentalists in the
The nature of the LSD experience.
  • J. Terrill
  • Psychology, Medicine
    The Journal of nervous and mental disease
  • 1962
TLDR
The most significant effects of the drug seemed to occur when S was allowed to follow his own spontaneous train of thought, and the technique of administration used with most of Ss is based on an attempt to provide a relatively permissive, comfortable and accepting atmosphere.
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance
TLDR
When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences, and the ability to occasion such experiences prospectively will allow rigorous scientific investigations of their causes and consequences.
Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects
TLDR
Under supportive conditions, 20 and 30 mg/70 kg psilocybin occasioned mystical-type experiences having persisting positive effects on attitudes, mood, and behavior.
Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness
TLDR
Assessment of the effect of psilocybin on changes in the five broad domains of personality – Neuroticism, Extroversion, Openness, Agreeableness, and Conscientiousness found significant increases in Openness following a high-dose p silocybin session.
...
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2
3
4
5
...