LRRfinder2.0: a webserver for the prediction of leucine-rich repeats.

  title={LRRfinder2.0: a webserver for the prediction of leucine-rich repeats.},
  author={Victoria Offord and Dirk Werling},
  journal={Innate immunity},
  volume={19 4},
Leucine-rich repeats (LRRs) are versatile motifs present in more than 6000 proteins throughout the phylogenetic kingdom. Tandem LRRs generate a characteristic horseshoe with a diverse range of functions. Fulfilling a key role in the innate immune system, LRRs form the TLR and NOD-like receptor (NLR) pathogen-recognition domain. Host-pathogen interactions mediated by LRRs drive those involved in ligand recognition to become distinct from their consensus motif. Most LRRs range between 21 and 30… CONTINUE READING

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