LRRK2 and Parkinson disease.

  title={LRRK2 and Parkinson disease.},
  author={Justus Alfred Daechsel and Matthew John Farrer},
  journal={Archives of neurology},
  volume={67 5},
OBJECTIVES To review the molecular genetics and functional biology of leucine-rich repeat kinase 2 (LRRK2) in parkinsonism and to summarize the opportunities and challenges to develop interventions for Parkinson disease (PD) based on this genetic insight. DATA SOURCES Publications cited are focused on LRRK2 biology between 2004 and March 2009. STUDY… CONTINUE READING