LRP10 in autosomal‐dominant Parkinson's disease
@article{Chen2019LRP10IA, title={LRP10 in autosomal‐dominant Parkinson's disease}, author={You Chen and Zhidong Cen and Xiaosheng Zheng and Qinqing Pan and Xinhui Chen and Lili Zhu and Si Chen and Hongwei Wu and Fei Xie and Haotian Wang and Dehao Yang and Lebo Wang and Baorong Zhang and Wei Luo}, journal={Movement Disorders}, year={2019}, volume={34} }
Recently, the LRP10 gene has been identified as a novel genetic cause in individuals affected by Parkinson's disease (PD), Parkinson's disease dementia, or dementia with Lewy bodies.
14 Citations
Analysis of the LRP10 gene in patients with Parkinson’s disease and dementia with Lewy bodies from Southern Italy
- Psychology, BiologyNeurological Sciences
- 2020
Recently, the LRP10 gene has been associated with Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD), and dementia with Lewy bodies (DLB). The aim of the present study was to evaluate…
Screening of LRP10 mutations in Parkinson's disease patients from Italy.
- Medicine, BiologyParkinsonism & related disorders
- 2021
Genetics of Parkinson's disease
- BiologyActa Neurologica Belgica
- 2020
A comprehensive overview on PD genetics is provided to provide a comprehensive overview of the genetic architecture underlying this disease as families harboring rare genetic variants are sparse and globally widespread.
Role of LRP10 in Parkinson's disease in a Taiwanese cohort.
- Medicine, BiologyParkinsonism & related disorders
- 2021
Clinical and Pathological Phenotypes of LRP10 Variant Carriers with Dementia
- Medicine, BiologyJournal of Alzheimer's disease : JAD
- 2020
Findings suggest a role for LRP10 across a broad neurodegenerative spectrum as well as some patients with dementia and different brain pathologies including DLB, mixed AD/LBD, and AD.
Mutation analysis of LRP10 in a large Chinese familial Parkinson disease cohort
- BiologyNeurobiology of Aging
- 2021
Genetics of Parkinson's disease: An introspection of its journey towards precision medicine
- BiologyNeurobiology of Disease
- 2020
LRP10 Mutations May Correlate with Sporadic Parkinson’s Disease in China
- Biology, MedicineMolecular neurobiology
- 2020
This study provides genetic evidence that LRP10 defects may correlate with sporadic Parkinson’s disease and identifies five variants that were predicted to be disease-causing or damaging by multiple in silico tools.
Rare, pathogenic variants in LRP10 are associated with amyotrophic lateral sclerosis in patients from mainland China
- Biology, MedicineNeurobiology of Aging
- 2021
Monogenic Parkinson’s Disease: Genotype, Phenotype, Pathophysiology, and Genetic Testing
- Biology, MedicineGenes
- 2022
It is highlighted that monogenic Parkinson’s disease is influenced by ethnicity and geographical differences, reinforcing the need for global efforts to pool large numbers of patients and identify novel candidate genes.
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