LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

@article{Quadri2018LRP10,
  title={
 LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study},
  author={M. Quadri and W. Mandemakers and Martyna M. Grochowska and R. Masius and Piero Parchi and International Parkinsonism Genetics Network},
  journal={The Lancet Neurology},
  year={2018},
  volume={17},
  pages={597-608}
}
BACKGROUND Most patients with Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies do not carry mutations in known disease-causing genes. The aim of this study was to identify a novel gene implicated in the development of these disorders. METHODS Our study was done in three stages. First, we did genome-wide linkage analysis of an Italian family with dominantly inherited Parkinson's disease to identify the disease locus. Second, we sequenced the candidate gene in an… Expand
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  • F. Morgante, E. Valente
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  • Movement disorders : official journal of the Movement Disorder Society
  • 2019
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Analysis of the LRP10 gene in patients with Parkinson’s disease and dementia with Lewy bodies from Southern Italy
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