LRP-1: A Checkpoint for the Extracellular Matrix Proteolysis

@article{Etique2013LRP1AC,
  title={LRP-1: A Checkpoint for the Extracellular Matrix Proteolysis},
  author={Nicolas Etique and L. Verzeaux and S. Dedieu and H. Emonard},
  journal={BioMed Research International},
  year={2013},
  volume={2013}
}
  • Nicolas Etique, L. Verzeaux, +1 author H. Emonard
  • Published 2013
  • Medicine, Biology
  • BioMed Research International
  • Low-density lipoprotein receptor-related protein-(LRP-1) is a large endocytic receptor that binds more than 35 ligands and exhibits signaling properties. Proteinases capable of degrading extracellular matrix (ECM), called matrix proteinases in this paper, are mainly serine proteinases: the activators of plasminogen into plasmin, tissue-type (tPA) and urokinase-type (uPA) plasminogen activators, and the members of the matrix metalloproteinase (MMP) family. LRP-1 is responsible for clearing… CONTINUE READING
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