LPS and neuroinflammation: a matter of timing

  title={LPS and neuroinflammation: a matter of timing},
  author={Patricia Castro Lopes},
Lipopolysaccharide (LPS) administration has been repeatedly shown to elicit central inflammation, regardless of the route of administration. In a recent study, Tiwari et al. (Inflammopharmacology 10.1007/s10787-016-0274-3 , 2016) dispute the potential of peripheral administration of LPS to induce neuroinflammation. Here, I summarise literature indicating that the neuroinflammatory effects of LPS are time dependent, and suggest that their findings can be explained by the time at which they chose… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications referenced by this paper.
Showing 1-10 of 22 references

2016), where peripheral LPS administration was employed and respective examples of the alteration in the neuroinflammatory markers quantified LPS doses

View 9 Excerpts
Highly Influenced

Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge : importance of CCR 2 / CCL 2 signaling

L Fan, T Wang, +3 authors D Ma
J Neuroinflamm • 2014

Similar Papers

Loading similar papers…