LPS and neuroinflammation: a matter of timing

@article{Lopes2016LPSAN,
  title={LPS and neuroinflammation: a matter of timing},
  author={Patricia Castro Lopes},
  journal={Inflammopharmacology},
  year={2016},
  volume={24},
  pages={291-293}
}
Lipopolysaccharide (LPS) administration has been repeatedly shown to elicit central inflammation, regardless of the route of administration. In a recent study, Tiwari et al. (Inflammopharmacology 10.1007/s10787-016-0274-3 , 2016) dispute the potential of peripheral administration of LPS to induce neuroinflammation. Here, I summarise literature indicating that the neuroinflammatory effects of LPS are time dependent, and suggest that their findings can be explained by the time at which they chose… CONTINUE READING

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