LONG-TERM FORGETTING IN PRECLINICAL FAMILIAL ALZHEIMER'S DISEASE

@inproceedings{Weston2016LONGTERMFI,
  title={LONG-TERM FORGETTING IN PRECLINICAL FAMILIAL ALZHEIMER'S DISEASE},
  author={Philip S.J. Weston and Yuying Liang and Susie M. D. Henley and Jennifer M. Nicholas and Natalie Sarah Ryan and Jonathan M. Schott and Martin Rossor and Christopher Collett Butler and Adam Zeman and Nick C. Fox},
  year={2016}
}
In Alzheimer9s disease (AD), detecting presymptomatic cognitive change has proven difficult. Accelerated long-term forgetting has been identified in other diseases involving the temporal lobe, in individuals who perform normally on standard cognitive testing. We assessed whether accelerated long-term forgetting is a feature of presymptomatic familial AD (FAD). We recruited 21 asymptomatic carriers of autosomal dominant FAD mutations (mean years to predicted onset=7.2) and 11 non-carrier… CONTINUE READING