LOGICOIL - multi-state prediction of coiled-coil oligomeric state

  title={LOGICOIL - multi-state prediction of coiled-coil oligomeric state},
  author={Thomas L. Vincent and Peter J. Green and Derek N. Woolfson},
  volume={29 1},
MOTIVATION The coiled coil is a ubiquitous α-helical protein-structure domain that directs and facilitates protein-protein interactions in a wide variety of biological processes. At the protein-sequence level, the coiled coil is readily recognized via a conspicuous heptad repeat of hydrophobic and polar residues. However, structurally coiled coils are more complicated, existing in a wide range of oligomer states and topologies. As a consequence, predicting these various states from sequence… CONTINUE READING
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