LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".

Abstract

Reid and Nicchitta propose that most cellular translation is carried out by a noncycling pool of endoplasmic reticulum (ER)-associated ribosomes. However, proximity-specific ribosome profiling data place an upper bound of about 7 to 16% on the fraction of cytosolic protein translation carried out by ribosomes accessible to ER-tethered biotin ligases… (More)
DOI: 10.1126/science.aaa8299

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@article{Jan2015LOCALTR, title={LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".}, author={Calvin H. Jan and Christopher J. C. Williams and Jonathan S. Weissman}, journal={Science}, year={2015}, volume={348 6240}, pages={1217} }