LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis

@inproceedings{Tong2010LOC387715HTRA1GP,
  title={LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis},
  author={Yu Neng Tong and J. Q. Liao and Yuan Zhang and Jing Zhou and Hengyu Zhang and Meng Mao},
  booktitle={Molecular vision},
  year={2010}
}
PURPOSE To examine the association of age-related macular degeneration (AMD) with HtrA serine peptidase 1 (HTRA1) gene rs11200638 G→A polymorphism and LOC387715/ ARMS2 gene rs10490924 G→T polymorphisms, and to evaluate the magnitude of the gene effect and the possible genetic mode of action. METHODS We searched the US National Library of Medicine's PubMed, Embase, OMIM, ISI Web of Science, and CNKI databases in a systematic manner to retrieve all genetic association studies on the HTRA1… CONTINUE READING