LMOf2365_0442 Encoding for a Fructose Specific PTS Permease IIA May Be Required for Virulence in L. monocytogenes Strain F2365

@article{Liu2017LMOf2365\_0442EF,
  title={LMOf2365\_0442 Encoding for a Fructose Specific PTS Permease IIA May Be Required for Virulence in L. monocytogenes Strain F2365},
  author={Yanhong Liu and Brian B. Yoo and Cheng‐An Hwang and Yujuan Suo and Shiowshuh Sheen and Parvaneh Khosravi and Lihan Huang},
  journal={Frontiers in Microbiology},
  year={2017},
  volume={8}
}
Listeria monocytogenes is a foodborne pathogen that causes listeriosis, which is a major public health concern due to the high fatality rate. LMOf2365_0442, 0443, and 0444 encode for fructose-specific EIIABC components of phosphotransferase transport system (PTS) permease that is responsible for sugar transport. In previous studies, in-frame deletion mutants of a putative fructose-specific PTS permease (LMOf2365_0442, 0443, and 0444) were constructed and analyzed. However, the virulence… Expand
6 Citations
Contributions of a LysR Transcriptional Regulator to Listeria monocytogenes Virulence and Identification of Its Regulons
TLDR
It is shown that lysR contributes to Listeria pathogenesis and replication in cell lines and is highlighted in regulating the transcription of genes involved in different pathways that might be essential for growth and persistence of L. monocytogenes in the host or under nutrient limitation. Expand
The influence of enzyme EII of the cellobiose-phosphotransferase system on the virulence of Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus)
TLDR
After the deletion of cel-EII complexes, the biological characteristics of THN0901 and TFJ0901 were consistent, including their cellobiose metabolism, and their biofilm formation abilities were significantly reduced. Expand
Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency
TLDR
Evidence of impairment in plaque formation in environmental isolates of B. pseudomallei is revealed that is associated with large genomic loss of genes important for intracellular multiplication and MNGC formation, suggesting that the genomic and phenotypic differences of environmental isolate may be associated with clinical infection. Expand
Proteomic analysis of Listeria monocytogenes exposed to free and nanostructured antimicrobial lipopeptides.
TLDR
The sugar and oligopeptide transporters regulated by antimicrobial action may influence the key virulence factor PrfA, reducing the pathogenicity of this microorganism. Expand
Genome-Wide Analyses Revealed Remarkable Heterogeneity in Pathogenicity Determinants, Antimicrobial Compounds, and CRISPR-Cas Systems of Complex Phytopathogenic Genus Pectobacterium
TLDR
Detailed genome-wide comparative analyses of twelve species that conform the Pectobacterium genus decipher the different strategies that each species has developed to infect their hosts, outcompete for food resources, and defend against bacteriophages. Expand
Draft Whole-Genome Sequences of Seven Listeria monocytogenes Strains with Variations in Virulence and Stress Responses
TLDR
The draft genome sequences of seven L. monocytogenes strains isolated from food, environmental, and clinical sources help in understanding why these strains displayed different virulence and stress response characteristics. Expand

References

SHOWING 1-10 OF 41 REFERENCES
Construction of Listeria monocytogenes mutants with in-frame deletions in the phosphotransferase transport system (PTS) and analysis of their growth under stress conditions.
TLDR
The results indicate that deletion mutants of the PTS genes were more resistant to multiple stress conditions compared to the wild-type, suggesting that they may contribute to the general stress response in L. monocytogenes. Expand
Regulation of Mannose Phosphotransferase System Permease and Virulence Gene Expression in Listeria monocytogenes by the EIItMan Transporter
TLDR
Results show that EIItMan participates to various extents in glucose-mediated CCR of PTS operons and makes a small, albeit significant, contribution to downregulation of virulence gene transcription by glucose in strain EGD-e. Expand
Cellobiose-Specific Phosphotransferase System of Klebsiella pneumoniae and Its Importance in Biofilm Formation and Virulence
TLDR
The celB locus of K. pneumoniae may contribute to biofilm formation and virulence through the metabolism of cellobiose, and is implicated in reduced susceptibility to the host immune response. Expand
Carbon‐source regulation of virulence gene expression in Listeria monocytogenes
TLDR
Results are consistent with a model in which PrfA activity is controlled by interaction with a hypothetical cofactor, the synthesis or depletion of which is responsive to the presence of readily metabolized carbohydrates, and suggest that NCTC7973 may be a partially deregulated variant. Expand
The major PEP-phosphotransferase systems (PTSs) for glucose, mannose and cellobiose of Listeria monocytogenes, and their significance for extra- and intracellular growth.
TLDR
The PEP-dependent phosphotransferase systems of Listeria monocytogenes EGD-e are examined, especially those involved in glucose and cellobiose transport, and replication of both mutants within epithelial cells or macrophages is as efficient as that of the wild-type strain. Expand
Role of Flagellin and the Two-Component CheA/CheY System of Listeria monocytogenes in Host Cell Invasion and Virulence
ABSTRACT The flagellum protein flagellin of Listeria monocytogenes is encoded by the flaA gene. Immediately downstream of flaA, two genes, cheY and cheA, encoding products with homology to chemotaxisExpand
Identification of Listeria monocytogenes Genes Contributing to Intracellular Replication by Expression Profiling and Mutant Screening
TLDR
Evidence is provided that L. monocytogenes can use alternative carbon sources like phosphorylated glucose and glycerol and nitrogen sources like ethanolamine during replication in epithelial cells and that the pentose phosphate cycle, but not glycolysis, is the predominant pathway of sugar metabolism in the host environment. Expand
Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species.
TLDR
W Whole genome comparative analyses revealed that the L.monocytogenes genomes are essentially syntenic, with the majority of genomic differences consisting of phage insertions, transposable elements and SNPs. Expand
A Mariner Transposon-Based Signature-Tagged Mutagenesis System for the Analysis of Oral Infection by Listeria monocytogenes
TLDR
A novel signature-tagged mutagenesis (STM) system based upon a mariner transposon to favour numerous and random transposition events throughout the L. monocytogenes genome is designed and it is proposed that this represents an optimised STM system for functional genetic analysis of foodborne/oral infection by L.monocyTogenes. Expand
Gene expression profiling of a pressure-tolerant Listeria monocytogenes Scott A ctsR deletion mutant
TLDR
Understanding of how Listeria monocytogenes survives under HHP is enhanced and may contribute to the design of effective and economically feasible HHP treatment in food processing. Expand
...
1
2
3
4
5
...