LMO3 interacts with p53 and inhibits its transcriptional activity.

Abstract

High expression of LMO3 contributes to the development and aggressiveness of neuroblastoma. LMO3 belongs to the LIM-only protein family, in which de-regulation of its members is implicated in human carcinogenesis. However, the molecular mechanism of LMO3 activity in oncogenesis remained poorly characterized. We found that LMO3 is a direct interacting… (More)
DOI: 10.1016/j.bbrc.2009.12.010

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