LIPID ADJUVANTS AND ANTIGENS EMBEDDED IN THE MYCOBACTERIAL CELL ENVELOPE

@inproceedings{Layre2014LIPIDAA,
  title={LIPID ADJUVANTS AND ANTIGENS EMBEDDED IN THE MYCOBACTERIAL CELL ENVELOPE},
  author={Emilie Layre},
  year={2014}
}
The mycobacterial granuloma is one of the most complex and anatomically de ned immunological lesions in medicine, composed of concentric rings of necrosis, myeloid palisade, peripheral lymphocytes and polymorphonuclear phagocytes. In vaccine design, mycobacterial cell walls, also known as Freund’s adjuvant, have been widely used to stimulate T-cell responses in experiments over the last century. These two widely known immunological phenomena indicate that mycobacteria normally generate immune… CONTINUE READING

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