LINEs, SINEs and processed pseudogenes: parasitic strategies for genome modeling

@article{Dewannieux2005LINEsSA,
  title={LINEs, SINEs and processed pseudogenes: parasitic strategies for genome modeling},
  author={Marie Dewannieux and Thierry Heidmann},
  journal={Cytogenetic and Genome Research},
  year={2005},
  volume={110},
  pages={35 - 48}
}
Two major classes of retrotransposons have invaded eukaryotic genomes: the LTR retrotransposons closely resembling the proviral integrated form of infectious retroviruses, and the non-LTR retrotransposons including the widespread, autonomous LINE elements. Here, we review the modeling effects of the latter class of elements, which are the most active in humans, and whose enzymatic machinery is subverted to generate a large series of “secondary” retroelements. These include the processed… 
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TLDR
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Novel Role of 3’UTR-Embedded Alu Elements as Facilitators of Processed Pseudogene Genesis and Host Gene Capture by Viral Genomes
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A novel role for Alu or Alu-like elements inside 3’UTRs as facilitators of the genesis of PPs, particularly in lowly expressed genes is suggested.
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