LIMIX : genetic analysis of multiple traits

  title={LIMIX : genetic analysis of multiple traits},
  author={Christoph Lippert and Franceso Paolo Casale and Barbara Rakitsch and Oliver Stegle},
Multi-trait mixed models have emerged as a promising approach for joint analyses of multiple traits. In principle, the mixed model framework is remarkably general. However, current methods implement only a very specific range of tasks to optimize the necessary computations. Here, we present a multi-trait modeling framework that is versatile and fast: LIMIX enables to flexibly adapt mixed models for a broad range of applications with different observed and hidden covariates, and variable study… CONTINUE READING


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