LIM kinase 2 is widely expressed in all tissues.

  title={LIM kinase 2 is widely expressed in all tissues.},
  author={Karla Acevedo and Nathalie Moussi and Rong Tao Li and Priscilla Soo and Ora Bernard},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  volume={54 5},
The LIM kinase family includes two proteins: LIMK1 and LIMK2. These proteins have identical genomic structure and overall amino acid identity of 50%. Both proteins regulate actin polymerization via phosphorylation and inactivation of the actin depolymerizing factors ADF/cofilin. Although the function of endogenous LIMK1 is well established, little is known about the function of the endogenous LIMK2 protein. To understand the specific role of endogenous LIMK2 protein, we examined its expression… CONTINUE READING


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