LIF (AM424), a promising growth factor for the treatment of ALS.

@article{Kurek1998LIFA,
  title={LIF (AM424), a promising growth factor for the treatment of ALS.},
  author={John B. Kurek and Allyn Radford and Doug Crump and John J. Bower and Sandra J Feeney and Leanne Austin and Edward Byrne},
  journal={Journal of the neurological sciences},
  year={1998},
  volume={160 Suppl 1},
  pages={S106-13}
}
Growth factors are theoretically promising agents for ALS therapy, but have been disappointing in subcutaneous delivery due to either toxicity or lack of major efficacy. Leukaemia inhibitory factor (LIF), was named after its effect on haemopoietic cells, and belongs to a group of cytokines which includes CNTF, IL-6, CT-1, OM and IL-11. All group members use… CONTINUE READING