LETTERS Irregular presence of abnormal prion protein in appendix in variant Creutzfeldt-Jakob disease

  • Published 2002


We have investigated the presence of disease related prion protein (PrP) in appendix samples obtained at necropsy from four neuropathologically confirmed cases of variant Creutzfeldt-Jakob disease (vCJD). PrP was detected in only one vCJD appendix, at a level lower than found in a diagnostic tonsil biopsy sample obtained from the same patient. The single… (More)


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