LDL receptor and Pcsk9 transcripts are decreased in liver of ovariectomized rats: effects of exercise training.

@article{Sock2014LDLRA,
  title={LDL receptor and Pcsk9 transcripts are decreased in liver of ovariectomized rats: effects of exercise training.},
  author={Emilienne Tudor Ngo Sock and Natalie Ann Chapados and J. M. Lavoie},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2014},
  volume={46 8},
  pages={550-5}
}
The aim of this study was to determine the effects of ovariectomy in rats on hepatic gene expression of key molecules involved in cholesterol metabolism and to verify if exercise training may play a role in preventing hypercholesterolemia in Ovx rats. Sprague-Dawley rats were ovariectomized (Ovx) or sham-operated (Sham) and were either trained (Tr) on treadmill or kept sedentary (Sed) for 8 weeks. Rats were divided into 5 groups: Sham-Sed, Sham-Tr, Ovx-Sed, Ovx-Tr and Ovx with 17β-estradiol… CONTINUE READING

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