LCZ696 : a new paradigm for the treatment of heart failure?


INTRODUCTION Heart failure (HF) represents a significant healthcare issue because of its ever-increasing prevalence, poor prognosis and complex pathophysiology. Currently, blockade of the renin-angiotensin-aldosterone system (RAAS) is the cornerstone of treatment; however, the combination of RAAS blockade with inhibition of neprilysin (NEP), an enzyme that… (More)
DOI: 10.1517/14656566.2015.1000300


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