LC3B is indispensable for selective autophagy of p62 but not basal autophagy.

@article{Maruyama2014LC3BII,
  title={LC3B is indispensable for selective autophagy of p62 but not basal autophagy.},
  author={Yoko Maruyama and Yu-shin Sou and Shun Kageyama and Takao Takahashi and Takashi Ueno and Keiji Tanaka and M. Asaliaru Komatsu and Yoshinobu Ichimura},
  journal={Biochemical and biophysical research communications},
  year={2014},
  volume={446 1},
  pages={
          309-15
        }
}
Autophagy is a unique intracellular protein degradation system accompanied by autophagosome formation. Besides its important role through bulk degradation in supplying nutrients, this system has an ability to degrade certain proteins, organelles, and invading bacteria selectively to maintain cellular homeostasis. In yeasts, Atg8p plays key roles in both autophagosome formation and selective autophagy based on its membrane fusion property and interaction with autophagy adaptors/specific… CONTINUE READING

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