LC-MS-based metabonomics analysis.

  title={LC-MS-based metabonomics analysis.},
  author={Xin Lu and XinJie Zhao and Changmin Bai and Chunxia Zhao and Guo Lu and Guowang Xu},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  volume={866 1-2},
Metabonomics aims at the comprehensive and quantitative analysis of wide arrays of metabolites in biological samples. It has shown particular promise in the areas of toxicology and drug development, functional genomics, systems biology, and clinical diagnosis. Comprehensive metabonomics investigations are primarily a challenge for analytical chemistry. High-performance liquid chromatography-mass spectrometry (HPLC-MS) is an established technology in drug metabolite analysis and is now expanding… CONTINUE READING

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