LC-MS/MS method for the determination of melamine in rat plasma: toxicokinetic study in Sprague-Dawley rats.

@article{Yang2009LCMSMSMF,
  title={LC-MS/MS method for the determination of melamine in rat plasma: toxicokinetic study in Sprague-Dawley rats.},
  author={Feng Yang and Yu Mao and Xiaodong Zhang and Zhiqiang Ma and Xiaochao Zhang},
  journal={Journal of separation science},
  year={2009},
  volume={32 17},
  pages={
          2974-8
        }
}
Most recently, melamine has raised international concern for its catastrophic health effects stemming from tainted infant formula. So far there is limited information concerning the pharmacokinetics of melamine in mammals. The present report concerns the development and validation of a sensitive HPLC-ESI-MS/MS method for the pharmacokinetic study of melamine in rat. The method employed a simple liquid-liquid extraction process for plasma sample cleanup, and the extraction recoveries of melamine… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Similar Papers

Loading similar papers…