LC-MS/MS Quantification of Zn- 2 Glycoprotein: A Potential Serum Biomarker for Prostate Cancer


Background: Zn2 glycoprotein (ZAG) is a relatively abundant glycoprotein that has potential as a biomarker for prostate cancer. We present a high-flow liquid chromatography–tandem mass spectrometry (LC-MS/MS) method for measuring serum ZAG concentrations by proteolytic cleavage of the protein and quantification of a unique peptide. Methods: We selected the… (More)


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