LC/ESI-MS method for the determination of trimetazidine in human plasma: application to a bioequivalence study on Chinese volunteers.

Abstract

A rapid liquid chromatography electrospray ionization mass spectrometry (LC/ESI-MS) method with good sensitivity and specificity has been developed and validated for the identification and quantification of trimetazidine in human plasma. Trimetazidine and lidocaine (internal standard) were isolated from plasma samples by protein precipitation with methanol… (More)

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@article{Jiao2007LCESIMSMF, title={LC/ESI-MS method for the determination of trimetazidine in human plasma: application to a bioequivalence study on Chinese volunteers.}, author={Yang Jiao and Mingming Su and Minjun Chen and Wei Jia and Yiqun Chou and Zhongyi Huang and Nanlin Yang and Weida Tong}, journal={Journal of pharmaceutical and biomedical analysis}, year={2007}, volume={43 5}, pages={1804-7} }