LANTCET: elimination of solid tumor cells with photothermal bubbles generated around clusters of gold nanoparticles.

@article{Hleb2008LANTCETEO,
  title={LANTCET: elimination of solid tumor cells with photothermal bubbles generated around clusters of gold nanoparticles.},
  author={Ekaterina Y Hleb and Jason H Hafner and Jeffrey N. Myers and Ehab Y Hanna and Betty C Rostro and Sergey A Zhdanok and Dmitri O. Lapotko},
  journal={Nanomedicine},
  year={2008},
  volume={3 5},
  pages={647-67}
}
BACKGROUND We have developed a method, termed laser-activated nano-thermolysis as a cell elimination technology (LANTCET), for the selective detection and destruction of individual tumor cells by the generation of intracellular photothermal bubbles around clusters of gold nanoparticles. METHOD Bare nanoparticles and their conjugates to C225 tumor-specific monoclonal antibodies were applied in vitro to C225-positive squamous carcinoma cells and in vivo to an experimental tumor in a rat in… CONTINUE READING
27 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…