LAMB3 is associated with disease progression and cisplatin cytotoxic sensitivity in head and neck squamous cell carcinoma.

@article{Liu2018LAMB3IA,
  title={LAMB3 is associated with disease progression and cisplatin cytotoxic sensitivity in head and neck squamous cell carcinoma.},
  author={Lihua Liu and Seung-Nam Jung and Chan Ho Oh and Kyungmin Lee and Ho-Ryun Won and Jae Won Chang and Jin man Kim and Bon Seok Koo},
  journal={European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology},
  year={2018}
}
OBJECTIVES Laminin subunit beta-3 (LAMB3) is a major component of the basement membrane zone. In our study, we investigated the role of LAMB3 in head and neck squamous cell carcinoma (HNSCC) progression and its clinical implication as a prognostic biomarker. MATERIALS AND METHODS A retrospective analysis of 100 patients with HNSCC who had undergone curative surgery from 1999 to 2011 was performed. We evaluated LAMB3 expression by immunohistochemistry and its associations with… CONTINUE READING
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