L1 interaction domains of papillomavirus l2 necessary for viral genome encapsidation.

@article{Okun2001L1ID,
  title={L1 interaction domains of papillomavirus l2 necessary for viral genome encapsidation.},
  author={M M Okun and Patricia M. Day and Heather L. Greenstone and Frank P. Booy and Douglas R Lowy and John T. Schiller and Richard B S Roden},
  journal={Journal of virology},
  year={2001},
  volume={75 9},
  pages={4332-42}
}
BPHE-1 cells, which harbor 50 to 200 viral episomes, encapsidate viral genome and generate infectious bovine papillomavirus type 1 (BPV1) upon coexpression of capsid proteins L1 and L2 of BPV1, but not coexpression of BPV1 L1 and human papillomavirus type 16 (HPV16) L2. BPV1 L2 bound in vitro via its C-terminal 85 residues to purified L1 capsomers, but not with intact L1 virus-like particles in vitro. However, when the efficiency of BPV1 L1 coimmunoprecipitation with a series of BPV1 L2… CONTINUE READING
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