L1 cell adhesion molecule (L1CAM) is a strong predictor for locoregional recurrences in cervical cancer

  title={L1 cell adhesion molecule (L1CAM) is a strong predictor for locoregional recurrences in cervical cancer},
  author={Marlies Schrevel and Willem E Corver and Margit E. Vegter and Natalja Tatjana ter Haar and Enno J. Dreef and Jogchum Jan Beltman and Gemma G Kenter and Tjalling Bosse and Cornelis D. de Kroon and Ekaterina S Jordanova},
Background L1 cell adhesion molecule (L1CAM) has been shown to be a prognostic marker in various cancer types, and has been suggested to play a role in epithelial mesenchymal transition (EMT). Here, we determined the prognostic significance of L1CAM in cervical cancer and its association with vimentin expression on tumor cells, indicative of EMT. Methods Formalin-fixed, paraffin-embedded primary tumor samples from 372 cervical cancer patients were collected for immunohistochemical analysis of… CONTINUE READING
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