L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth

@article{Schmid2008L1AN,
  title={L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth},
  author={Ralf S Schmid and Patricia Ann Fults Maness},
  journal={Current Opinion in Neurobiology},
  year={2008},
  volume={18},
  pages={245-250}
}
Neural cell adhesion molecules (CAMs) of the immunoglobulin superfamily engage in multiple neuronal interactions that influence cell migration, axonal and dendritic projection, and synaptic targeting. Their downstream signal transduction events specify whether a cell moves or projects axons and dendrites to targets in the brain. Many of the diverse functions of CAMs are brought about through homophilic and heterophilic interactions with other cell surface receptors. An emerging concept is that… CONTINUE READING
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