L-glutamine in vitro regulates rat aortic glutamate content and modulates nitric oxide formation and contractility responses.

@article{Schachter2007LglutamineIV,
  title={L-glutamine in vitro regulates rat aortic glutamate content and modulates nitric oxide formation and contractility responses.},
  author={D. Schachter},
  journal={American journal of physiology. Cell physiology},
  year={2007},
  volume={293 1},
  pages={
          C142-51
        }
}
  • D. Schachter
  • Published 2007
  • Biology, Medicine
  • American journal of physiology. Cell physiology
These studies test the hypothesis that l-glutamine at its physiological plasma concentration, approximately 0.5 mM, can increase tissue content and net synthesis of glutamate in rat aortic segments in vitro, thereby mediating relaxation of the underlying smooth muscle in the elastic reservoir region of the thoracic aorta. Aortic segments were incubated in an isotonic medium with and without 21 amino acids at their normal plasma concentrations. Of these amino acids only L-glutamine and L-leucine… Expand
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