L-glutamate conditionally modulates the K+ current of Müller glial cells.

  title={L-glutamate conditionally modulates the K+ current of M{\"u}ller glial cells.},
  author={E. A. Schwartz},
  volume={10 6},
L-Glutamate inhibits the K+ conductance that dominates the electrical behavior of a Müller glial cell. The effect of glutamate is enhanced by simultaneous exposure to dopamine. L-Glutamate acts at a metabotropic receptor that controls the K+ conductance through two pathways. A rapid pathway produces a partial inhibition in less than 2 s. Thereafter, a slow pathway progressively inhibits the conductance with a half-time of minutes. Pathways initiated by L-glutamate and dopamine appear to… CONTINUE READING